Microplate nephelometer for light-scattering and turbidity measurements
The world’s first and only laser-based microplate nephelometer was developed to meet high-throughput demands for fast compound solubility screens. The NEPHELOstar® Plus detects insoluble particles in liquid samples by measuring forward scattered light and can be used for turbidity measurements, drug solubility screening, protein binding kinetics, microbial growth, and petroleum process control.
|Nephelometry (light scattering)|
|Endpoint and kinetic|
|Up to 384-well plates|
PhotodiodeWavelength 635±10 nm
|Side window photodiode detector|
Up to 2 built-in reagent injectors
Injection at measurement position (6 to 384-well)
Individual injection volumes for each well (3 to 500 µL)
Variable injection speed up to 420 µL / s
Up to four injection events per wellReagent back flushing
Depend on assay conditions and liquid surface stabilityShortest times possible: 16 s (96), 47 s (384)
|Linear, orbital, and double-orbital with user-definable time and speed|
+4°C above ambient up to 45°C or 60°CThe upper heating plate of the incubation chamber operates at 0.5°C more than the lower plate. This prevents condensation build-up on the lid or sealer.